InvivoGen提供多種重組細胞因子，包括干擾素、白介素、生長/集落刺激因子、類激素細胞因子和腫瘤壞死因子相關細胞因子。我們的細胞因子來源于大腸桿菌和/或哺乳動物細胞表達系統。各個批次的產品均使用對應的報告細胞以及中和抗體進行功能測試和炎癥。InvivoGen的重組細胞因子以極-具競爭力的價格提供卓-越的品質。
主要特點
• 來源于大腸桿菌或哺乳動物細胞（CHO或HEK293）
• 保證生物活性
• 高純度
• 徹-底純化，不含內毒素
• 嚴格的質量控制
應 用
• 細胞因子檢測和定量分析標準品
• 中和抗體篩選和釋放分析
• 工程化細胞因子篩選和釋放分析
| 產品 | 描述 | 貨號 |
| 源自大腸桿菌的細胞因子 | ||
| Recombinant human CD40L | E. coli-derived recombinant human cytokine,tag-free, with HSA | rcyec-hcd401 |
| Recombinant human G-CSF | E. coli-derived recombinant human cytokine,tag-free, carrier-free | rcyec-hgcsf |
| Recombinant human GM-CSF | E. coli-derived recombinant human cytokine, tag-free, carrier-free | rcyec-hgmcsf |
| Recombinant human IFN-Y | E. coli-derived recombinant human cytokine,tag-free, with HSA | rcyec-hifng |
| Recombinant human IL-1β | E. coli-derived recombinant human cytokine,tag-free, with HSA | rcyec-hil1b |
| Recombinant human IL-3 | E. coli-derived recombinant human cytokine,tag-free, carrier-free | rcyec-hil3 |
| Recombinant human IL-4 | E. coli-derived recombinant human cytokine,tag-free, with HSA | rcyec-hil4 |
| Recombinant human IL-6 | E. coli-derived recombinant human cytokine, tag-free, with HSA | rcyec-hil6 |
| Recombinant human IL-18 | E. coli-derived recombinant human cytokine,tag-free, with HSA | rcyec-hil18 |
| Recombinant human IL-21 | E. coli-derived recombinant human cytokine, tag-free, carrier-free | rcyec-hil21 |
| Recombinant human IL-31 | E. coli-derived recombinant human cytokine,tag-free, carrier-free | rcyec-hil31 |
| Recombinant human IL-33 | E. coli-derived recombinant human cytokine,tag-free, carrier-free | rcyec-hil33 |
| Recombinant human IL-36a | E. coli-derived recombinant human cytokine,tag-free, carrier-free | rcyec-hil36a |
| Recombinant human RANKL | E. coli-derived recombinant human cytokine,tag-free, carrier-free | rcyec-hrankl |
| 為您的抗體研究選擇合適的細胞因子來源 |  |
| 針對不同實驗目標，InvivoGen提供產自大腸桿菌或哺乳動物細胞的高質量重組細胞因子，價格極-具競爭力。 • 產自大腸桿菌的細胞因子 是早期抗體篩選的理想選擇（如特異性或結合分析）。一些細胞因子沒有天然的的復雜糖基化，因此可以由大腸桿菌產生正確折疊且具有生物活性的細胞因子。這些細胞因子常被用作免疫原，以從小鼠或兔子體內獲取特異性單克隆抗體(mAb)。然而，用于治療的重組mAb必須用哺乳動物細胞產生的細胞因子進行測試，以確保其有效靶向和中和人類的靶標。 • 產自哺乳動物的細胞因子 具有天然的3D折疊和翻譯后修飾，例如糖基化和二硫鍵模式，這些模式在細菌中難以或不可能重現。通過選擇CHO或HEK293表達的細胞因子，可以加速從早期篩選到臨床開發的過渡。 | |
| 特色產品 | |
| RECOMBINANT HUMAN IL-18 | RECOMBINANT HUMAN IL-1β |
 |  |
| (A) HEK-BlueTM IL-18 and (B) HEK-BlueTM IL-1β cells were stimulated with increasing concentrations of human (h)IL-18 (produced in E. coli), or hIL-1β (produced in E. coli or CHO cells), respectively. After overnight incubation, the NF-κB-induced SEAP activity was determined using QUANTI-Blue™, a SEAP detection reagent. Data are shown as optical density (OD) at 650 nm (mean ± SEM). | |
| 相關產品 | 貨號 | |
| Cytokine Agonist Screening Service | cytk-ago | |
| B18R-IFN-a/β inhibitor | inh-b18r | |
| B8R-IFN-y inhibitor | inh-b8r | |
| 產品 | 描述 | 貨號 |
| CYTOKINES PRODUCED IN CHO/HEK293 CELLS | ||
| Recombinant human APRIL | HEK293-derived recombinant human cytokine, His-tag, carrier-free | rcyc-hapril-hs |
| Recombinant human BAFF | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hbaff |
| Recombinant human CD40L | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hcd40l |
| Recombinant human EPO | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hepo |
| Recombinant human GM-CSF | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hgmcsf |
| Recombinant human IFN-α2b | CHO-derived recombinant human cytokine, tag-free, with HSA | rcyc-hifna2b-1 |
| Recombinant human IFN-α10 | CHO-derived recombinant human cytokine, tag-free, with HSA | rcyc-hifna10-1 |
| Recombinant human IL-1β | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil1b |
| Recombinant human IL-2 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil2-01 |
| Recombinant human IL-4 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil4 |
| Recombinant human IL-5 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil5 |
| Recombinant human IL-7 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil7 |
| Recombinant human IL-9 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil9 |
| Recombinant human IL-10 | HEK293-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil10 |
| Recombinant human IL-11 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil11 |
| Recombinant human IL-12 | CHO-derived recombinant human cytokine, tag-free, with HSA | rcyc-hil12 |
| Recombinant human IL-13 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil13 |
| Recombinant human IL-15 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil15 |
| Recombinant human IL-16 | HEK293-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil16-01 |
| Recombinant mouse IL-16 | HEK293-derived recombinant mouse cytokine, tag-free, carrier-free | rcyc-mil16-01 |
| Recombinant human IL-17A | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil17a |
| Recombinant human IL-20 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil20 |
| Recombinant human IL-22 | HEK293-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil22 |
| Recombinant human IL-23 | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hill23 |
| Recombinant human IL-25 | HEK293-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil25 |
| Recombinant human IL-29 | HEK293-derived recombinant human cytokine, tag-free, carrier-free | rcyc-hil29 |
| Recombinant human TGF-β | HEK293-derived recombinant human cytokine, tag-free, with HSA | rcyc-htgfb1 |
| Recombinant human TL1A | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-htl1a |
| Recombinant human TNF-α | CHO-derived recombinant human cytokine, tag-free, with HSA | rcyc-htnfa |
| Recombinant human TPO | CHO-derived recombinant human cytokine, tag-free, carrier-free | rcyc-htpo |
| Recombinant human TSLP | CHO-derived recombinant human cytokine, His-tag, carrier-free | rcyc-htslp-hs |
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