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Antimycin A

更新時(shí)間:2022-01-28

簡(jiǎn)要描述:

Antibiotic. Induces apoptosis, which is not prevented by the presence of Bcl-2. Inhibits mitochondrial electron transport specifically between cytochromes b and c1.

型號(hào):廠商性質(zhì):代理商瀏覽量:1052


Antibiotic. Induces apoptosis, which is not prevented by the presence of Bcl-2. Inhibits mitochondrial electron transport specifically between cytochromes b and c1.

Product Details

Alternative Name:Antipiricullin, Virosin

Source:Isolated from Streptomyces sp. Mixture of antimycin A's.

CAS:1397-94-0

MI:14: 714 (A1) & 715 (A3)

RTECS:CD0350000

Appearance:White to faint yellow powder.

Solubility:Soluble in 100% ethanol (50mg/ml).

Shipping:Ambient

Long Term Storage:-20°C

Handling:Protect from light.

Regulatory Status:RUO - Research Use Only

ALX-380-075
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ALX-380-075


Product Literature References

Unexpected Role of Sterol Synthesis in RNA Stability and Translation in Leishmania: Z. N. Karamysheva, et al.; Biomedicines 19, 696 (2021), Abstract;
COQ11 deletion mitigates respiratory deficiency caused by mutations in the gene encoding the coenzyme Q chaperone protein Coq10: M.C. Bradley, et al.; J. Biol. Chem. 295, 6023 (2020), Abstract; Full Text
UBXD1 is a mitochondrial recruitment factor for p97/VCP and promotes mitophagy: A.C. Bento, et al.; Sci. Rep. 8, 12415 (2018), Abstract; Full Text
The Natural Product Mensacarcin Induces Mitochondrial Toxicity and Apoptosis in Melanoma Cells: B. Plitzko, et al.; J. Biol. Chem. 292, 21102 (2017), Abstract; Full Text
The effect of phosphate availability on chondrocyte metabolic function: K. Blank, et al.; (2016), (master's thesis), Application(s): Inhibitor of complex III in the electron transport chain, Full Text
An ROS generator, antimycin A, inhibits the growth of HeLa cells via apoptosis: W.H. Park, et al.; J. Cell. Biochem. 102, 98 (2007), Abstract;
Oligomycin and antimycin A prevent nitric oxide-induced apoptosis by blocking cytochrome C leakage: N. Dairaku, et al.; J. Lab. Clin. Med. 143, 143 (2004), Abstract;
Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3: S.P. Tzung, et al.; Nat. Cell Biol. 3, 183 (2001), Abstract;
Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3: S.P. Tzung, et al.; Nat. Cell. Biol. 3, 183 (2001), Abstract;
Biophysical characterization of recombinant human Bcl-2 and its interactions with an inhibitory ligand, antimycin A: K.M. Kim, et al.; Biochemistry 40, 4911 (2001), Abstract;
Synthetic peptides and non-peptidic molecules as probes of structure and function of Bcl-2 family proteins and modulators of apoptosis: D. Liu & Z. Huang; Apoptosis 6, 453 (2001), Abstract;
The effect of antimycin A on mouse liver inner mitochondrial membrane channel activity: M.L. Campo, et al.; J. Biol. Chem. 267, 8123 (1992), Abstract; Full Text
The isolation and properties of antimycin A: B. R. Dunshee, et al.; J. Am. Chem. Soc. 71, 2436 (1949),


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